38 search results - page 1 / 8 » Pfam: multiple sequence alignments and HMM-profiles of prote... |
NAR
1998
13 years 4 months ago
1998
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
RECOMB
2003
Springer
14 years 5 months ago
2003
Springer
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
BMCBI
2006
13 years 4 months ago
2006
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
BMCBI
2008
13 years 5 months ago
2008
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
ECCB
2008
IEEE
13 years 11 months ago
2008
IEEE
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...