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» Phylogenetics by likelihood: Evolutionary modeling as a tool...
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BMCBI
2008
130views more  BMCBI 2008»
13 years 5 months ago
IDEA: Interactive Display for Evolutionary Analyses
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...
BMCBI
2010
153views more  BMCBI 2010»
13 years 5 months ago
VITCOMIC: visualization tool for taxonomic compositions of microbial communities based on 16S rRNA gene sequences
Background: Understanding the community structure of microbes is typically accomplished by sequencing 16S ribosomal RNA (16S rRNA) genes. These community data can be represented b...
Hiroshi Mori, Fumito Maruyama, Ken Kurokawa
BMCBI
2008
111views more  BMCBI 2008»
13 years 5 months ago
GENOMEPOP: A program to simulate genomes in populations
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Antonio Carvajal-Rodríguez
IJDMB
2010
61views more  IJDMB 2010»
13 years 4 months ago
On a novel coalescent model for genome-wide evolution of Copy Number Variations
: Since we are limited in our knowledge of human demographic history and variations of recombination and mutation rates, large-scale computer simulation is a necessary tool in gene...
Antonina Mitrofanova, Bhubaneswar (Bud) Mishra
BMCBI
2007
247views more  BMCBI 2007»
13 years 5 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai