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» Physical Mapping of Chromosomes Using Unique Probes
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BMCBI
2005
104views more  BMCBI 2005»
13 years 4 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
BMCBI
2007
110views more  BMCBI 2007»
13 years 4 months ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison
BMCBI
2011
12 years 12 months ago
CODA (CrossOver Distribution Analyzer): quantitative characterization of crossover position patterns along chromosomes
Background: During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distribute...
Franck Gauthier, Olivier C. Martin, Matthieu Falqu...
BIBE
2007
IEEE
148views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A New Smoothing Model for Analyzing Array CGH Data
—Array based Comparative Genomic Hybridization (CGH) is a molecular cytogenetic method for the detection of chromosomal imbalances and it has been extensively used for studying c...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
ISAAC
2004
Springer
153views Algorithms» more  ISAAC 2004»
13 years 10 months ago
Canonical Data Structure for Interval Probe Graphs
The class of interval probe graphs is introduced to deal with the physical mapping and sequencing of DNA as a generalization of interval graphs. The polynomial time recognition al...
Ryuhei Uehara