Sciweavers

6 search results - page 1 / 2
» Predicting Bevirimat resistance of HIV-1 from genotype
Sort
View
BMCBI
2010
57views more  BMCBI 2010»
13 years 4 months ago
Predicting Bevirimat resistance of HIV-1 from genotype
Background: Maturation inhibitors are a new class of antiretroviral drugs. Bevirimat (BVM) was the first substance in this class of inhibitors entering clinical trials. While the ...
Dominik Heider, Jens Verheyen, Daniel Hoffmann
BMCBI
2010
156views more  BMCBI 2010»
13 years 4 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
BMCBI
2010
135views more  BMCBI 2010»
13 years 4 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
ECAI
2006
Springer
13 years 8 months ago
Abductive Logic Programming in the Clinical Management of HIV/AIDS
Abstract. This paper presents a new Abductive Logic Programming (ALP) approach for assisting clinicians in the selection of antiretroviral drugs for patients infected with Human Im...
Oliver Ray, Athos Antoniades, Antonis C. Kakas, Io...
CCGRID
2005
IEEE
13 years 10 months ago
A grid-based HIV expert system
ABSTRACT. Objectives. This paper addresses Grid-based integration and access of distributed data from infectious disease patient databases, literature on in-vitro and in-vivo pharm...
Peter M. A. Sloot, Alexander Boukhanovsky, Wilco K...