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BMCBI
2006
158views more  BMCBI 2006»
13 years 5 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
RECOMB
2006
Springer
14 years 5 months ago
RNA Secondary Structure Prediction Via Energy Density Minimization
Abstract. There is a resurgence of interest in RNA secondary structure prediction problem (a.k.a. the RNA folding problem) due to the discovery of many new families of non-coding R...
Can Alkan, Emre Karakoç, Süleyman Cenk...
RECOMB
2005
Springer
14 years 5 months ago
Consensus Folding of Unaligned RNA Sequences Revisited
As one of the earliest problems in computational biology, RNA secondary structure prediction (sometimes referred to as "RNA folding") problem has attracted attention agai...
Vineet Bafna, Haixu Tang, Shaojie Zhang
BMCBI
2004
116views more  BMCBI 2004»
13 years 5 months ago
Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure p
Background: A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy mini...
Kishore J. Doshi, Jamie J. Cannone, Christian W. C...