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BMCBI
2010
177views more  BMCBI 2010»
13 years 5 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
EVOW
2008
Springer
13 years 7 months ago
Protein Interaction Inference Using Particle Swarm Optimization Algorithm
Many processes in the cell involve interaction among the proteins and determination of the networks of such interactions is of immense importance towards the complete understanding...
Mudassar Iqbal, Alex Alves Freitas, Colin G. Johns...
NAR
2007
65views more  NAR 2007»
13 years 4 months ago
STRING 7 - recent developments in the integration and prediction of protein interactions
Information on protein–protein interactions is still mostly limited to a small number of model organisms, and originates from a wide variety of experimental and computational te...
Christian von Mering, Lars Juhl Jensen, Michael Ku...
ALMOB
2006
109views more  ALMOB 2006»
13 years 5 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2006
144views more  BMCBI 2006»
13 years 5 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...