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» Predicting phenotype from patterns of annotation
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BMCBI
2005
151views more  BMCBI 2005»
13 years 5 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang
SDM
2007
SIAM
107views Data Mining» more  SDM 2007»
13 years 7 months ago
On Demand Phenotype Ranking through Subspace Clustering
High throughput biotechnologies have enabled scientists to collect a large number of genetic and phenotypic attributes for a large collection of samples. Computational methods are...
Xiang Zhang, Wei Wang 0010, Jun Huan
ISMB
2000
13 years 7 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu
BMCBI
2011
13 years 24 days ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
BMCBI
2010
179views more  BMCBI 2010»
13 years 5 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...