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» Prediction of MHC class I binding peptides, using SVMHC
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BMCBI
2002
51views more  BMCBI 2002»
13 years 4 months ago
Prediction of MHC class I binding peptides, using SVMHC
Pierre Dönnes, Arne Elofsson
RECOMB
2005
Springer
14 years 5 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz
BMCBI
2008
115views more  BMCBI 2008»
13 years 4 months ago
Improving peptide-MHC class I binding prediction for unbalanced datasets
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
Ana Paula Sales, Georgia D. Tomaras, Thomas B. Kep...
BMCBI
2010
106views more  BMCBI 2010»
13 years 4 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2010
109views more  BMCBI 2010»
13 years 4 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann