A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
We consider the prediction of a target’s destination and simultaneously recover its filtered trajectory. Two novel models for trajectories with known destinations are presented...
Mustafa Fanaswala, Vikram Krishnamurthy, Langford ...
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
Kasper Munch, Paul P. Gardner, Peter Arctander, An...
We have recently proposed an EM-style algorithm to optimize log-linear models with hidden variables. In this paper, we use this algorithm to optimize a hidden conditional random ...
Georg Heigold, Stefan Hahn, Patrick Lehnen, Herman...