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BMCBI
2007
126views more  BMCBI 2007»
13 years 5 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2006
129views more  BMCBI 2006»
13 years 5 months ago
BIPAD: A web server for modeling bipartite sequence elements
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Chengpeng Bi, Peter K. Rogan
ROCAI
2004
Springer
13 years 11 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
ALMOB
2006
135views more  ALMOB 2006»
13 years 5 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 5 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li