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JIB
2006
78views more  JIB 2006»
13 years 4 months ago
Prediction of transcription factor binding to DNA using rule induction methods
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Mikael Huss, Karin Nordström
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
Fernando Garcia-Alcalde, Armando Blanco, Adrian J....
BMCBI
2005
130views more  BMCBI 2005»
13 years 4 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
PRIB
2010
Springer
123views Bioinformatics» more  PRIB 2010»
13 years 3 months ago
Machine Learning Study of DNA Binding by Transcription Factors from the LacI Family
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
Gennady G. Fedonin, Mikhail S. Gelfand
BIOINFORMATICS
2012
11 years 7 months ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...