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» Prediction of twin-arginine signal peptides
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BMCBI
2005
85views more  BMCBI 2005»
13 years 4 months ago
Prediction of twin-arginine signal peptides
Background: Proteins carrying twin-arginine (Tat) signal peptides are exported into the periplasmic compartment or extracellular environment independently of the classical Secdepe...
Jannick Dyrløv Bendtsen, Henrik Nielsen, Da...
ICASSP
2009
IEEE
13 years 11 months ago
Conditional random fields for the prediction of signal peptide cleavage sites
Correct prediction of signal peptide cleavage sites has a significant impact on drug design. State-of-the-art approaches to cleavage site prediction typically use generative mode...
Man-Wai Mak, Sun-Yuan Kung
EVOW
2010
Springer
13 years 11 months ago
A Local Search Appproach for Transmembrane Segment and Signal Peptide Discrimination
Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Sami Laroum, Dominique Tessier, Béatrice Du...
ISMB
1998
13 years 6 months ago
Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
Henrik Nielsen, Anders Krogh
BMCBI
2010
107views more  BMCBI 2010»
12 years 11 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy