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» Prediction of twin-arginine signal peptides
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BMCBI
2005
85views more  BMCBI 2005»
13 years 10 months ago
Prediction of twin-arginine signal peptides
Background: Proteins carrying twin-arginine (Tat) signal peptides are exported into the periplasmic compartment or extracellular environment independently of the classical Secdepe...
Jannick Dyrløv Bendtsen, Henrik Nielsen, Da...
ICASSP
2009
IEEE
14 years 5 months ago
Conditional random fields for the prediction of signal peptide cleavage sites
Correct prediction of signal peptide cleavage sites has a significant impact on drug design. State-of-the-art approaches to cleavage site prediction typically use generative mode...
Man-Wai Mak, Sun-Yuan Kung
EVOW
2010
Springer
14 years 5 months ago
A Local Search Appproach for Transmembrane Segment and Signal Peptide Discrimination
Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Sami Laroum, Dominique Tessier, Béatrice Du...
ISMB
1998
14 years 3 days ago
Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
Henrik Nielsen, Anders Krogh
BMCBI
2010
107views more  BMCBI 2010»
13 years 5 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy