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BIOINFORMATICS
2007
190views more  BIOINFORMATICS 2007»
13 years 5 months ago
Towards clustering of incomplete microarray data without the use of imputation
Motivation: Clustering technique is used to find groups of genes that show similar expression patterns under multiple experimental conditions. Nonetheless, the results obtained by...
Dae-Won Kim, Ki Young Lee, Kwang H. Lee, Doheon Le...
BMCBI
2007
138views more  BMCBI 2007»
13 years 5 months ago
A full Bayesian hierarchical mixture model for the variance of gene differential expression
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...
Samuel O. M. Manda, Rebecca E. Walls, Mark S. Gilt...
BIBE
2007
IEEE
155views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Partial Mixture Model for Tight Clustering in Exploratory Gene Expression Analysis
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Yinyin Yuan, Chang-Tsun Li
EVOW
2004
Springer
13 years 10 months ago
Evolutionary Search of Thresholds for Robust Feature Set Selection: Application to the Analysis of Microarray Data
Abstract. We deal with two important problems in pattern recognition that arise in the analysis of large datasets. While most feature subset selection methods use statistical techn...
Carlos Cotta, Christian Sloper, Pablo Moscato
CSDA
2007
151views more  CSDA 2007»
13 years 5 months ago
Robust semiparametric mixing for detecting differentially expressed genes in microarray experiments
An important goal of microarray studies is the detection of genes that show significant changes in observed expressions when two or more classes of biological samples such as tre...
Marco Alfò, Alessio Farcomeni, Luca Tardell...