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CLUSTER
2007
IEEE
14 years 16 days ago
Sequential and parallel implementation of a constraint-based algorithm for searching protein structures
— Data mining in biological structure libraries can be a powerful tool to better understand biochemical processes. This article introduces the LISA algorithm which enables the re...
Sascha Hunold, Thomas Rauber, Georg Wille
BMCBI
2006
178views more  BMCBI 2006»
13 years 6 months ago
MannDB - A microbial database of automated protein sequence analyses and evidence integration for protein characterization
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...
Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam...
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 11 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BMCBI
2006
166views more  BMCBI 2006»
13 years 6 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
13 years 11 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald