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» Probabilistic Model Checking of Complex Biological Pathways
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CMSB
2006
Springer
13 years 8 months ago
Probabilistic Model Checking of Complex Biological Pathways
Abstract. Probabilistic model checking is a formal verification technique that has been successfully applied to the analysis of systems from a broad range of domains, including sec...
John Heath, Marta Z. Kwiatkowska, Gethin Norman, D...
SIGMETRICS
2008
ACM
130views Hardware» more  SIGMETRICS 2008»
13 years 4 months ago
Using probabilistic model checking in systems biology
Probabilistic model checking is a formal verification framework for systems which exhibit stochastic behaviour. It has been successfully applied to a wide range of domains, includ...
Marta Z. Kwiatkowska, Gethin Norman, David Parker
CMSB
2009
Springer
13 years 11 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
ENTCS
2007
119views more  ENTCS 2007»
13 years 4 months ago
PML: Toward a High-Level Formal Language for Biological Systems
Documentation of knowledge about biological pathways is often informal and vague, making it difficult to efficiently synthesize the work of others into a holistic understanding of...
Bor-Yuh Evan Chang, Manu Sridharan
BIBE
2007
IEEE
113views Bioinformatics» more  BIBE 2007»
13 years 10 months ago
Quantitative and Probabilistic Modeling in Pathway Logic
—This paper presents a study of possible extensions of Pathway Logic to represent and reason about semiquantitative and probabilistic aspects of biological processes. The underly...
Alessandro Abate, Yu Bai, Nathalie Sznajder, Carol...