12 search results - page 1 / 3 » Probabilistic Paths for Protein Complex Inference |
RECOMB
2006
Springer
14 years 9 months ago
2006
Springer
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
RECOMB
2008
Springer
14 years 9 months ago
2008
Springer
The protein inference problem represents a major challenge in shotgun proteomics. Here we describe a novel Bayesian approach to address this challenge that incorporates the predict...
NIPS
2004
13 years 10 months ago
2004
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
BMCBI
2007
2007
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
13 years 9 months ago
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
NIPS
2004
13 years 10 months ago
2004
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...