Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann
The correct interpretation of tandem mass spectra is a difficult problem, even when it is limited to scoring peptides against a database. De novo sequencing is considerably harder...
Glycans are molecules made from simple sugars that form complex tree structures. Glycans constitute one of the most important protein modifications, and identification of glycans...