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IDEAL
2007
Springer
13 years 11 months ago
PINCoC : A Co-clustering Based Approach to Analyze Protein-Protein Interaction Networks
A novel technique to search for functional modules in a protein-protein interaction network is presented. The network is represented by the adjacency matrix associated with the und...
Clara Pizzuti, Simona E. Rombo
BMCBI
2010
112views more  BMCBI 2010»
13 years 5 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
ICML
2009
IEEE
14 years 6 months ago
A Bayesian approach to protein model quality assessment
Given multiple possible models b1, b2, . . . bn for a protein structure, a common sub-task in in-silico Protein Structure Prediction is ranking these models according to their qua...
Hetunandan Kamisetty, Christopher James Langmead
BMCBI
2007
97views more  BMCBI 2007»
13 years 5 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2006
165views more  BMCBI 2006»
13 years 5 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...