Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
The prediction of protein secondary structure is a classical problem in bioinformatics, and in the past few years several machine learning techniques have been proposed to t. From...