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» Protein Folding Simulation in CCP
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BMCBI
2008
130views more  BMCBI 2008»
13 years 6 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
BMCBI
2010
116views more  BMCBI 2010»
13 years 6 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
RECOMB
2006
Springer
14 years 6 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
BIOSYSTEMS
2007
109views more  BIOSYSTEMS 2007»
13 years 6 months ago
Protein folding and the robustness of cells
The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of mole...
G. J. Shawn Tan, Ferran D. Revilla, Klaus-Peter Za...
CANDC
2006
ACM
13 years 6 months ago
Hydrophobic collapse in (in silico) protein folding
A model of hydrophobic collapse, which is treated as the driving force for protein folding, is presented. This model is the superposition of three models commonly used in protein ...
Michal Brylinski, Leszek Konieczny, Irena Roterman