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» Protein homology detection using string alignment kernels
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BIOINFORMATICS
2004
46views more  BIOINFORMATICS 2004»
13 years 5 months ago
Protein homology detection using string alignment kernels
Hiroto Saigo, Jean-Philippe Vert, Nobuhisa Ueda, T...
CIBCB
2005
IEEE
13 years 11 months ago
The Homology Kernel: A Biologically Motivated Sequence Embedding into Euclidean Space
— Part of the challenge of modeling protein sequences is their discrete nature. Many of the most powerful statistical and learning techniques are applicable to points in a Euclid...
Eleazar Eskin, Sagi Snir
ICPR
2008
IEEE
14 years 6 months ago
Fast protein homology and fold detection with sparse spatial sample kernels
In this work we present a new string similarity feature, the sparse spatial sample (SSS). An SSS is a set of short substrings at specific spatial displacements contained in the or...
Pai-Hsi Huang, Pavel P. Kuksa, Vladimir Pavlovic
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 5 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
BMCBI
2006
120views more  BMCBI 2006»
13 years 5 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu