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BMCBI
2006
74views more  BMCBI 2006»
13 years 4 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
BMCBI
2004
150views more  BMCBI 2004»
13 years 4 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2006
117views more  BMCBI 2006»
13 years 4 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
SNPD
2004
13 years 6 months ago
Prediction of Protein Dispensability through Integrated Analysis of Multiple-Source High-Throughput Data
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating ...
Yu Chen, Dong Xu
RECOMB
2005
Springer
14 years 5 months ago
Comparison of Protein-Protein Interaction Confidence Assignment Schemes
Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing protein interaction networks for various species at a...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...