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CIBCB
2007
IEEE
13 years 9 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay
BMCBI
2010
159views more  BMCBI 2010»
13 years 5 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
CP
2003
Springer
13 years 10 months ago
Propagating N-Ary Rigid-Body Constraints
In this paper, we present an algorithm to propagate an n-ary constraint (with n greater than 2) specifying the relative positions of points in a three-dimensional rigid group. The ...
Ludwig Krippahl, Pedro Barahona
JCB
2007
144views more  JCB 2007»
13 years 4 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
RECOMB
2006
Springer
14 years 5 months ago
Detecting the Dependent Evolution of Biosequences
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...
Jeremy Darot, Chen-Hsiang Yeang, David Haussler