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BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 5 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
ICASSP
2008
IEEE
13 years 11 months ago
Probabilistic structural alignment of RNA sequences
We propose an algorithm for estimating the common secondary structure, alignment, and posterior base pairing probabilities for two RNA sequences. A definition of structural align...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
ICPR
2006
IEEE
14 years 6 months ago
Protein Fold Recognition using a Structural Hidden Markov Model
Protein fold recognition has been the focus of computational biologists for many years. In order to map a protein primary structure to its correct 3D fold, we introduce in this pa...
Djamel Bouchaffra, Jun Tan
AE
2005
Springer
13 years 10 months ago
Incorporating Knowledge of Secondary Structures in a L-System-Based Encoding for Protein Folding
An encoding scheme for protein folding on lattice models, inspired by parametric L-systems, was proposed. The encoding incorporates problem domain knowledge in the form of predesig...
Gabriela Ochoa, Gabi Escuela, Natalio Krasnogor
RECOMB
2009
Springer
14 years 5 months ago
Learning Models for Aligning Protein Sequences with Predicted Secondary Structure
Accurately aligning distant protein sequences is notoriously difficult. A recent approach to improving alignment accuracy is to use additional information such as predicted seconda...
Eagu Kim, Travis J. Wheeler, John D. Kececioglu