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ICASSP
2011
IEEE
12 years 8 months ago
A fully automated 2-DE gel image analysis pipeline for high throughput proteomics
Image analysis is still considered as the bottleneck in 2D-gel based expression proteomics analysis for biomarkers discovery. We are presenting a new end-to-end image analysis pip...
Panagiotis Tsakanikas, Elias S. Manolakos
BMCBI
2007
91views more  BMCBI 2007»
13 years 5 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas
BIB
2011
13 years 4 hour ago
Protein mass spectra data analysis for clinical biomarker discovery: a global review
The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. In recent years there has been a growing interest in using high ...
Pascal Roy, Caroline Truntzer, Delphine Maucort-Bo...
BMCBI
2010
109views more  BMCBI 2010»
13 years 5 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
BMCBI
2006
153views more  BMCBI 2006»
13 years 5 months ago
2DDB - a bioinformatics solution for analysis of quantitative proteomics data
Background: We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is ...
Lars Malmström, György Marko-Varga, Guni...