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» QOMA2: Optimizing the alignment of many sequences
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IEICET
2008
89views more  IEICET 2008»
13 years 5 months ago
Near-Optimal Block Alignments
Abstract-In this paper, we improve the idea of the near-optimal alignments. Though the near optimal alignments increase the possibility to find the correct alignment, too many of t...
Kuo-Tsung Tseng, Chang-Biau Yang, Kuo-Si Huang, Yu...
BMCBI
2005
142views more  BMCBI 2005»
13 years 4 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
GCB
2006
Springer
140views Biometrics» more  GCB 2006»
13 years 8 months ago
PALMA: Perfect Alignments using Large Margin Algorithms
: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequen...
Gunnar Rätsch, Bettina Hepp, Uta Schulze, Che...
BMCBI
2005
158views more  BMCBI 2005»
13 years 4 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
AAAI
2004
13 years 6 months ago
PROBCONS: Probabilistic Consistency-Based Multiple Alignment of Amino Acid Sequences
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
Chuong B. Do, Michael Brudno, Serafim Batzoglou