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IJCAI
2001
13 years 6 months ago
Qualitative Simulation of Genetic Regulatory Networks: Method and Application
Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simu...
Hidde de Jong, Michel Page, Céline Hernande...
JCB
2002
131views more  JCB 2002»
13 years 4 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
AB
2008
Springer
13 years 11 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
AAAI
1997
13 years 6 months ago
Model Decomposition and Simulation: A Component Based Qualitative Simulation Algorithm
Traditionally, qualitative simulation uses a global, state-based representation to describe the behavior of the modeled system. For larger, more complex systems this representatio...
Daniel J. Clancy, Benjamin Kuipers