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BMCBI
2005
107views more  BMCBI 2005»
13 years 5 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
BMCBI
2010
109views more  BMCBI 2010»
13 years 5 months ago
Structural alphabets derived from attractors in conformational space
Background: The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as `states'...
Alessandro Pandini, Arianna Fornili, Jens Kleinjun...
GECCO
2007
Springer
162views Optimization» more  GECCO 2007»
13 years 11 months ago
Using pair approximations to predict takeover dynamics in spatially structured populations
The topological properties of a network directly impact the flow of information through a system. For example, in natural populations, the network of inter-individual contacts aff...
Joshua L. Payne, Margaret J. Eppstein
RECOMB
2008
Springer
14 years 5 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
BMCBI
2011
13 years 8 days ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein