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» Quantitative analysis of EGR proteins binding to DNA: assess...
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BMCBI
2010
128views more  BMCBI 2010»
13 years 5 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
ISDA
2009
IEEE
14 years 13 days ago
Similarity Analysis of Protein Binding Sites: A Generalization of the Maximum Common Subgraph Measure Based on Quasi-Clique Dete
—Protein binding sites are often represented by means of graphs capturing their most important geometrical and physicochemical properties. Searching for structural similarities a...
Imen Boukhris, Zied Elouedi, Thomas Fober, Marco M...
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
Fernando Garcia-Alcalde, Armando Blanco, Adrian J....
BMCBI
2004
130views more  BMCBI 2004»
13 years 5 months ago
PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability
Background: Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which th...
Yanlin Huang, David Kowalski
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
13 years 9 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu