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BMCBI
2008
170views more  BMCBI 2008»
13 years 5 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
ICASSP
2008
IEEE
14 years 5 hour ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
BIBE
2004
IEEE
179views Bioinformatics» more  BIBE 2004»
13 years 9 months ago
Incorporating Ontology-Driven Similarity Knowledge into Functional Genomics: An Exploratory Study
This research explores the feasibility of semantic similarity approaches to supporting predictive tasks in functional genomics. It aims to establish potential relationships betwee...
Francisco Azuaje, Olivier Bodenreider
NAR
2011
194views Computer Vision» more  NAR 2011»
12 years 8 months ago
GreenPhylDB v2.0: comparative and functional genomics in plants
GreenPhylDB is a database designed for comparative and functional genomics based on complete genomes. Version 2 now contains sixteen full genomes of members of the plantae kingdom...
Mathieu Rouard, Valentin Guignon, Christelle Aluom...
BMCBI
2008
200views more  BMCBI 2008»
13 years 5 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia