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BMCBI
2007
200views more  BMCBI 2007»
13 years 5 months ago
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
Ágnes Baross, Allen D. Delaney, H. Irene Li...
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically drive
Background: Many programs have been developed to identify transcription factor binding sites. However, most of them are not able to infer two-word motifs with variable spacer leng...
Fabrice Touzain, Sophie Schbath, Isabelle Debled-R...
BMCBI
2008
88views more  BMCBI 2008»
13 years 5 months ago
Large-scale identification of polymorphic microsatellites using an in silico approach
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
Jifeng Tang, Samantha J. Baldwin, Jeanne M. E. Jac...
BMCBI
2007
156views more  BMCBI 2007»
13 years 5 months ago
Predictive modeling of plant messenger RNA polyadenylation sites
Background: One of the essential processing events during pre-mRNA maturation is the posttranscriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track pr...
Guoli Ji, Jianti Zheng, Yingjia Shen, Xiaohui Wu, ...