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BMCBI
2006
134views more  BMCBI 2006»
13 years 5 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BMCBI
2004
96views more  BMCBI 2004»
13 years 5 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2011
12 years 8 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
KDD
2003
ACM
113views Data Mining» more  KDD 2003»
14 years 5 months ago
Indexing multi-dimensional time-series with support for multiple distance measures
Although most time-series data mining research has concentrated on providing solutions for a single distance function, in this work we motivate the need for a single index structu...
Michail Vlachos, Marios Hadjieleftheriou, Dimitrio...
IPPS
1998
IEEE
13 years 9 months ago
Randomization in Parallel Stringology
In this abstract, we provide an overview of our survey of randomized techniques for exploiting the parallelism in string matching problems. Broadly, the study of string matching fa...
S. Muthukrishnan