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» RNA structure alignment by a unit-vector approach
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BIOSURVEILLANCE
2007
Springer
13 years 11 months ago
Detecting Conserved RNA Secondary Structures in Viral Genomes: The RADAR Approach
Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Mugdha Khaladkar, Jason T. L. Wang
BMCBI
2008
140views more  BMCBI 2008»
13 years 5 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2002
108views more  BMCBI 2002»
13 years 5 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
RECOMB
1998
Springer
13 years 9 months ago
A polyhedral approach to RNA sequence structure alignment
Ribonucleic acid (RNA) is a polymer composed of four bases denoted A, C, G, and U. It is a generally single-stranded molecule where the bases form hydrogen bonds within the same m...
Hans-Peter Lenhof, Knut Reinert, Martin Vingron
METMBS
2004
196views Mathematics» more  METMBS 2004»
13 years 6 months ago
An Open Problem in RNA Secondary Structure Prediction by the Comparative Approach
Abstract One approach to predict the secondary structure of RNA is the comparative approach. This approach is used when alignment of several homologous sequences of a RNA is availa...
Stefan Engelen, Fariza Tahi