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GCB
2010
Springer
198views Biometrics» more  GCB 2010»
13 years 2 months ago
RNALfoldz: Efficient Prediction of Thermodynamically Stable, Local Secondary Structures
Abstract: The search for local RNA secondary structures and the annotation of unusually stable folding regions in genomic sequences are two well motivated bioinformatic problems. I...
Andreas R. Gruber, Stephan H. F. Bernhart, You Zho...
NAR
2007
124views more  NAR 2007»
13 years 4 months ago
The RNAz web server: prediction of thermodynamically stable and evolutionarily conserved RNA structures
Many non-coding RNA genes and cis-acting regulatory elements of mRNAs contain RNA secondary structures that are critical for their function. Such functional RNAs can be predicted ...
Andreas R. Gruber, Richard Neuböck, Ivo L. Ho...
BMCBI
2007
94views more  BMCBI 2007»
13 years 4 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...