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» RNAMute: RNA Secondary Structure Mutation Analysis Tool
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BMCBI
2006
82views more  BMCBI 2006»
13 years 5 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BIBE
2003
IEEE
124views Bioinformatics» more  BIBE 2003»
13 years 10 months ago
Prediction of Contact Maps Using Support Vector Machines
Contact map prediction is of great interest for its application in fold recognition and protein 3D structure determination. In this paper we present a contact-map prediction algor...
Ying Zhao, George Karypis
BMCBI
2010
110views more  BMCBI 2010»
13 years 5 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...