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BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
A genetic ensemble approach for gene-gene interaction identification
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
Pengyi Yang, Joshua W. K. Ho, Albert Y. Zomaya, Bi...
IJCNN
2006
IEEE
13 years 11 months ago
P-SVM Variable Selection for Discovering Dependencies Between Genetic and Brain Imaging Data
— The joint analysis of genetic and brain imaging data is the key to understand the genetic underpinnings of brain dysfunctions in several psychiatric diseases known to have a st...
Johannes Mohr, Imke Puis, Jana Wrase, Sepp Hochrei...
BMCBI
2008
88views more  BMCBI 2008»
13 years 5 months ago
Large-scale identification of polymorphic microsatellites using an in silico approach
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
Jifeng Tang, Samantha J. Baldwin, Jeanne M. E. Jac...
GPEM
2007
119views more  GPEM 2007»
13 years 5 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
BMCBI
2011
13 years 8 days ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...