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» Refractoriness and Neural Precision
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ICA
2010
Springer
13 years 6 months ago
Recovering Spikes from Noisy Neuronal Calcium Signals via Structured Sparse Approximation
Two-photon calcium imaging is an emerging experimental technique that enables the study of information processing within neural circuits in vivo. While the spatial resolution of th...
Eva L. Dyer, Marco F. Duarte, Don H. Johnson, Rich...
BMCBI
2010
106views more  BMCBI 2010»
13 years 5 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2010
227views more  BMCBI 2010»
13 years 5 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2008
116views more  BMCBI 2008»
13 years 5 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
BMCBI
2008
77views more  BMCBI 2008»
13 years 5 months ago
Stochastic models for the in silico simulation of synaptic processes
Background: Research in life sciences is benefiting from a large availability of formal description techniques and analysis methodologies. These allow both the phenomena investiga...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...