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CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Relating transcription factors, modules of genes and cultivation conditions in Saccharomyces cerevisiae
Usually, the functionality of a module of co-expressed genes is derived from enrichment within the module of a particular gene annotation category. The systematic setup of the che...
Theo A. Knijnenburg, Marcel J. T. Reinders, J. M. ...
BMCBI
2007
186views more  BMCBI 2007»
13 years 4 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BMCBI
2004
146views more  BMCBI 2004»
13 years 4 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 4 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BIOADIT
2004
Springer
13 years 10 months ago
Analysis of Responses of Complex Bionetworks to Changes in Environmental Conditions
Abstract. The responses of flexible bionetworks to extreme environmental changes were studied in several microorganisms. Gene and metabolic networks markedly changed with osmotic ...
Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahis...