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BMCBI
2010
112views more  BMCBI 2010»
13 years 5 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
BMCBI
2007
113views more  BMCBI 2007»
13 years 5 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2006
116views more  BMCBI 2006»
13 years 5 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
TREC
2003
13 years 6 months ago
Report on the TREC 2003 Experiment: Genomic Track
After retrieval, this simple strategy yield to an important improvement of the average precision: from 17.02 up to 35.80. Task II. Our approach is based on argumentative structurin...
Patrick Ruch, Gilles Cohen, Frédéric...