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BIOCOMP
2006
13 years 6 months ago
Reverse Engineering Approach in Molecular Evolution: Simulation and Case Study with Enzyme Proteins
- We developed a method of reverse engineering to compare the behaviour the enzyme proteins with the existing standard concepts. Our work is based on the strong assumption from the...
Sukanya Manna, Cheng-Yuan Liou
BIOSYSTEMS
2007
109views more  BIOSYSTEMS 2007»
13 years 4 months ago
Protein folding and the robustness of cells
The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of mole...
G. J. Shawn Tan, Ferran D. Revilla, Klaus-Peter Za...
BMCBI
2008
189views more  BMCBI 2008»
13 years 4 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
ENTCS
2010
118views more  ENTCS 2010»
13 years 2 months ago
Fragments-based Model Reduction: Some Case Studies
Molecular biological models usually suffer from a dramatic combinatorial blow up. Indeed, proteins form complexes and can modify each others, which leads to the formation of a hug...
Jérôme Feret