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BIBM
2007
IEEE
110views Bioinformatics» more  BIBM 2007»
13 years 9 months ago
Risk Factor Searching Heuristics for SNP Case-Control Studies
This paper addresses the computational challenge facing association analysis of case-control studies
Dumitru Brinza, Alexander Zelikovsky
BIBE
2007
IEEE
110views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Discrete Methods for Association Search and Status Prediction in Genotype Case-Control Studies
Abstract—Recent improvements in high-throughput genotyping technology make possible genome-wide association studies and status prediction (classification) for common complex dis...
Dumitru Brinza, Alexander Zelikovsky
BMCBI
2005
157views more  BMCBI 2005»
13 years 5 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen