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BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
13 years 5 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
BIOINFORMATICS
2005
93views more  BIOINFORMATICS 2005»
13 years 5 months ago
Donuts, scratches and blanks: robust model-based segmentation of microarray images
Inner holes, artifacts and blank spots are common in microarray images, but current image analysis methods do not pay them enough attention. We propose a new robust model-based me...
Qunhua Li, Chris Fraley, Roger Eugene Bumgarner, K...
BMCBI
2008
162views more  BMCBI 2008»
13 years 5 months ago
Background correction using dinucleotide affinities improves the performance of GCRMA
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
BMCBI
2002
89views more  BMCBI 2002»
13 years 5 months ago
Sources of variability and effect of experimental approach on expression profiling data interpretation
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
BMCBI
2007
145views more  BMCBI 2007»
13 years 5 months ago
The utility of MAS5 expression summary and detection call algorithms
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...
Stuart D. Pepper, Emma K. Saunders, Laura E. Edwar...