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» Robust test method for time-course microarray experiments
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JCB
2002
93views more  JCB 2002»
13 years 4 months ago
Unfolding of Microarray Data
The use of DNA microarrays for the analysis of complex biological samples is becoming a mainstream part of biomedical research. One of the most commonly used methods compares the ...
Andrew B. Goryachev, Pascale F. Macgregor, Aled M....
RECOMB
2009
Springer
14 years 5 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
BMCBI
2008
95views more  BMCBI 2008»
13 years 4 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
BMCBI
2007
165views more  BMCBI 2007»
13 years 4 months ago
TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays
Background: A nearly complete collection of gene-deletion mutants (96% of annotated open reading frames) of the yeast Saccharomyces cerevisiae has been systematically constructed....
Chulyun Kim, Sangkyum Kim, Russell Dorer, Dan Xie,...
BMCBI
2006
153views more  BMCBI 2006»
13 years 4 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...