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» SIMAP - The similarity matrix of proteins
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BICOB
2010
Springer
13 years 3 months ago
Multiple Kernel Learning for Fold Recognition
Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
Huzefa Rangwala
BMCBI
2010
153views more  BMCBI 2010»
13 years 5 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2006
120views more  BMCBI 2006»
13 years 5 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
130views more  BMCBI 2006»
13 years 5 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
CEC
2005
IEEE
13 years 11 months ago
Multiobjective clustering around medoids
Abstract- The large majority of existing clustering algorithms are centered around the notion of a feature, that is, individual data items are represented by their intrinsic proper...
Julia Handl, Joshua D. Knowles