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» SKPDB: a structural database of shikimate pathway enzymes
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BMCBI
2007
104views more  BMCBI 2007»
13 years 5 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn
NAR
2007
145views more  NAR 2007»
13 years 4 months ago
HMDB: the Human Metabolome Database
The Human Metabolome Database (HMDB) is currently the most complete and comprehensive curated collection of human metabolite and human metabolism data in the world. It contains re...
David S. Wishart, Dan Tzur, Craig Knox, Roman Eisn...
JIB
2006
106views more  JIB 2006»
13 years 5 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BMCBI
2008
117views more  BMCBI 2008»
13 years 5 months ago
Using a logical model to predict the growth of yeast
Background: A logical model of the known metabolic processes in S. cerevisiae was constructed from iFF708, an existing Flux Balance Analysis (FBA) model, and augmented with inform...
Ken E. Whelan, Ross D. King
NAR
2006
87views more  NAR 2006»
13 years 5 months ago
From genomics to chemical genomics: new developments in KEGG
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interacti...
Minoru Kanehisa, Susumu Goto, Masahiro Hattori, Ki...