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» SNPs Problems, Complexity, and Algorithms
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CIBCB
2008
IEEE
13 years 11 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake
BMCBI
2004
133views more  BMCBI 2004»
13 years 5 months ago
Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction m
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
Yasuyuki Tomita, Shuta Tomida, Yuko Hasegawa, Yoic...
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
SPIRE
2010
Springer
13 years 3 months ago
Identifying SNPs without a Reference Genome by Comparing Raw Reads
Next generation sequencing (NGS) technologies are being applied to many fields of biology, notably to survey the polymorphism across individuals of a species. However, while single...
Pierre Peterlongo, Nicolas Schnel, Nadia Pisanti, ...
IWANN
2009
Springer
13 years 12 months ago
Data Mining in Complex Diseases Using Evolutionary Computation
Abstract. A new algorithm is presented for finding genotype-phenotype association rules from data related to complex diseases. The algorithm was based on Genetic Algorithms, a tech...
Vanessa Aguiar, Jose A. Seoane, Ana Freire, Cristi...