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» SNPs Problems, Complexity, and Algorithms
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RECOMB
2003
Springer
14 years 6 months ago
Large scale reconstruction of haplotypes from genotype data
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Eleazar Eskin, Eran Halperin, Richard M. Karp
BMCBI
2006
98views more  BMCBI 2006»
13 years 5 months ago
JLIN: A java based linkage disequilibrium plotter
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
RECOMB
2002
Springer
14 years 6 months ago
An Overview of Combinatorial Methods for Haplotype Inference
A current high-priority phase of human genomics involves the development of a full Haplotype Map of the human genome [23]. It will be used in large-scale screens of populations to...
Dan Gusfield
BMCBI
2006
135views more  BMCBI 2006»
13 years 5 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
ICIC
2007
Springer
13 years 12 months ago
An Improved Nested Partitions Algorithm Based on Simulated Annealing in Complex Decision Problem Optimization
: - This paper introduces the main ideas of the nested partitions (NP) method, analyses its efficiency theoretically and proposes the way to improve the optimization efficiency of ...
Yan Luo, Changrui Yu