Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Two efficient and complementary sampling algorithms are presented to explore the space of closed clash-free conformations of a flexible protein loop. The "seed sampling" ...
Peggy Yao, Ankur Dhanik, Nathan Marz, Ryan Propper...
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...