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WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
TMI
2010
155views more  TMI 2010»
13 years 4 days ago
Tubular Surface Segmentation for Extracting Anatomical Structures From Medical Imagery
Abstract--This work provides a model for tubular structures, and devises an algorithm to automatically extract tubular anatomical structures from medical imagery. Our model fits ma...
Vandana Mohan, Ganesh Sundaramoorthi, Allen Tannen...
BMCBI
2011
12 years 12 months ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
BMCBI
2011
12 years 9 months ago
Conotoxin Protein Classification Using Free Scores of Words and Support Vector Machines
Background: Conotoxin has been proven to be effective in drug design and could be used to treat various disorders such as schizophrenia, neuromuscular disorders and chronic pain. ...
Nazar Zaki, Stefan Wolfsheimer, Grégory Nue...
BMCBI
2011
12 years 9 months ago
A Beta-Mixture Model for Dimensionality Reduction, Sample Classification and Analysis
Background: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper ...
Kirsti Laurila, Bodil Oster, Claus L. Andersen, Ph...